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Interestingly, it was also found that compared to ABX group, the blood glucose level of mice in ABX_LET group increased significantly at 90 min and the area under the IPGTT curve showed a significant difference ( Figures 2D, E ), and a significant increase in fasting insulin level was observed in ABX_LET group compared to ABX group( Figure 2F ), which suggested other factors that affected the glucose metabolism of PCOS mice

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At 12 months, the mean weight change from baseline was ~5% of body weight, regardless of their diabetes status

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